Research Interests
Brice’s proposed doctoral research aims to improve our understanding of pain as a multiscale nervous-system phenomenon. He seeks to understand how biological signals are detected, transmitted, transformed, and maintained across levels of organization, from molecular interactions and sensory neurons to peripheral tissues and brain-wide circuits. His work in systems biology uses computational and data-driven approaches to connect mechanisms of peripheral neuropathy, pain persistence, treatment response, and neuropsychiatric disease. By integrating molecular, cellular, tissue-level, and neuroimaging data, his research aims to identify clearer disease states, better biomarkers, and more precise therapeutic strategies for conditions ranging from chronic pain to disorders of brain-circuit regulation.
Area of Specialization
- Pain detection, signaling, processing, and pathology
- Simulation of neural circuits
- Brain-inspired AI architectures
- Virtual cell simulation